In a surprising announcement, the Vatican has confirmed that Pope Leo XIV has undergone surgery for lung cancer, specifically involving the removal of the lower lobe of his right lung. At the age of 71, the pontiff’s diagnosis is particularly striking given that he has never smoked, which is often viewed as the primary risk factor for this disease.
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Experts, however, stress that lung cancer is not exclusive to smokers. According to Dr Sohaib Intiaz, Chief Medical Officer of PEOPLE Inc., lung cancer among non-smokers is increasingly recognised. If classified as a separate category, it would rank as the fifth most common cause of cancer mortality worldwide and the seventh most prevalent cancer overall. Concerningly, research indicates that 60 to 80 per cent of non-smokers diagnosed with lung cancer develop the same type as Pope Leo, known as lung adenocarcinoma.

Dr Intiaz elaborates on the potential causes of this condition, highlighting a mix of environmental exposures, genetic predispositions, and internal bodily processes. In many cases, however, an identifiable cause remains elusive. Adenocarcinoma is particularly associated with the outer portions of the lungs, where fine particulate matter and pollutants tend to accumulate. Dr Intiaz notes that this suggests the disease may stem more from environmental factors rather than the direct effects of smoking.

One significant environmental factor is radon exposure. This colourless, odourless gas is a by-product of uranium decay in soil and rock and can accumulate within buildings, particularly in poorly ventilated areas. This type of exposure poses a considerable risk, as the radiation emitted can damage the cells lining the lungs.
In addition to radon, other environmental risks include outdoor air pollution and indoor air quality issues, such as secondhand smoke or fumes from cooking oil heated to high temperatures. While the smoke from incense, often used in church settings, could potentially act as a carcinogen, its associated risk appears mainly to affect smokers, with no substantial evidence linking incense exposure to lung cancer in non-smokers.
Age itself is a considerable factor in lung cancer risk, particularly in non-smokers. Dr Intiaz explains that advancing age significantly raises the likelihood of developing the disease. The incidence of lung cancer rises markedly after the age of 60, making age one of the most significant predictors of lung cancer risk, irrespective of smoking history.
The Vatican has yet to provide details regarding Pope Leo’s prognosis or additional treatments. However, Dr Intiaz does indicate that early detection coupled with surgical intervention maximises the chances of a successful outcome. For cases of early-stage lung adenocarcinoma that have been fully removed through lobectomy, the prognosis is generally favourable with a realistic possibility of cure.
Dr Intiaz further explains that non-smokers often have advantages in terms of earlier detection and overall health, which can enhance their prospects for recovery. He notes that in the Pope’s situation, these factors could support a positive outlook for his future health.
As news of Pope Leo XIV’s health condition develops, the broader implications for lung cancer awareness among non-smokers will remain a topic of discussion. The incident serves as a reminder of the complexities surrounding lung cancer and the myriad factors that can contribute to its onset, regardless of an individual’s smoking history.
