Kris Jenner, the well-known matriarch of the Kardashian-Jenner clan, has recently opened up about her experiences with popular weight-loss drugs and the methods she now employs to maintain her youthful appearance. In a candid conversation on the SHE MD Podcast, Jenner shared her journey with GLP-1 medication Ozempic, reflecting on how it didn’t work for her and the alternative solutions she found.
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At the age of 70, Jenner admitted to trying Ozempic at a time when it was still relatively unknown. However, her experience with the medication was less than favourable. “I did not do, like, an Ozempic,” she remarked during the podcast. “I tried it once, and it made me really sick.” Her discomfort was significant enough that she felt unable to work, explaining how the nausea affected her daily life. Following her dissatisfaction with Ozempic, Jenner consulted with Dr. Thais Aliabadi, who encouraged her to explore other options.

With the guidance of her physician, Jenner examined various alternatives and ultimately found success with peptide injections, a rising trend in wellness circles. “I realised that a peptide injection was really great for me,” she revealed. Peptides, which are short chains of amino acids, are touted for a range of potential benefits, including weight loss and enhanced athletic performance. Although their popularity has surged, experts urge caution, noting that the side effects and the full scope of their effectiveness are still under investigation.
In addition to the injections, Jenner credits her health regimen to the supplements recommended by Aliabadi. “She advises me on which supplements to add to my diet, such as fish oils and omega-3s,” she explained. The changes in her diet and wellness routine, Jenner noted, provided her with increased energy, enabling her to juggle her responsibilities more effectively.
The reality television star also addressed the impact of more traditional cosmetic procedures. Jenner openly discussed the well-publicised facelift that she underwent in 2025, for which she expressed deep gratitude toward her surgeon, Dr. Steven Levine. “I had a very well-known facelift a year ago. So that was helpful,” she said, sharing her satisfaction with the results.
Recently, Jenner faced speculation from the media regarding her surgery, with some reports claiming that she was dissatisfied with the outcome. However, she took to her daughter Khloé Kardashian’s podcast, “Khloé in Wonderland,” to refute these claims, stating, “The headline right now is that I hate my facelift, which couldn’t be further from the truth. I love my facelift. I adore my doctor. I’m obsessed with him.” Her emphasis on the positive relationship with her surgeon highlights her commitment to her appearance and well-being.
In a previous interview with Vogue Arabia, Jenner articulated her motivations for aesthetic alterations, asserting, “I decided to do this facelift because I want to be the best version of myself, and that makes me happy.” Her journey reflects a broader dialogue about self-image and the lengths some individuals are willing to go to in order to maintain a youthful presence.
As the discourse surrounding celebrity beauty and wellness continues to evolve, Jenner’s openness about her experiences serves as a reminder of the varied paths one can take in pursuit of personal health and appearance goals. From her candid reflections on medication to the embrace of surgical enhancements, Jenner’s narrative exemplifies the complexities and considerations many grapple with in today’s society.
As she addresses both her physical health and aesthetic choices, her journey resonates with many and exemplifies the intricacies involved in self-care in the public eye. Whether through innovative treatments or traditional cosmetic procedures, Kris Jenner’s approach underscores her dedication to presenting the best version of herself to the world.
