A recent study has indicated that men face double the risk of dying from ‘broken heart syndrome’ compared to women. This revelation comes as a result of new research, which was published in the Journal of the American Heart Association (JAHA) on May 14. The study found that 11.2% of men succumb to this condition, known scientifically as takotsubo cardiomyopathy, in contrast to 5.5% of women. This syndrome is triggered by emotional or physical stress, such as the loss of a loved one or significant life events like divorce.
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Takotsubo cardiomyopathy leads to a weakening of the heart’s pumping function and produces symptoms resembling a heart attack, including chest pain and difficulty breathing. While the exact causes remain unclear, experts speculate that a surge of stress hormones, particularly adrenaline, may play a role in inducing the temporary tightening of the heart’s arteries. This scenario can result in fatal outcomes as evidenced by the study, where 6.6% of individuals with broken heart syndrome died from cardiogenic shock, a condition where the heart fails to pump enough blood effectively.
Notably, the study highlighted that men faced a higher mortality rate from ‘broken heart syndrome’ due to various complications. For instance, the findings revealed that 35.9% of individuals with this condition died from congestive heart failure, while others succumbed to atrial fibrillation, stroke, or cardiac arrest. Dr. Harmony Reynolds, the director of the Sarah Ross Soter Center for Women’s Cardiovascular Research at NYU Langone Health, emphasised that men experiencing takotsubo syndrome tend to have worse outcomes than women, indicating the need for enhanced support and intervention strategies.

The research, conducted on nearly 200,000 hospitalised individuals aged 18 and above in the US between 2016 and 2020, also showcased a concerning trend. Despite men having a higher mortality rate, the condition affected a larger percentage of women, with approximately 83% of hospitalized patients being female. Additionally, the study revealed that 6.5% of women with ‘broken heart syndrome’ faced a substantial mortality rate, indicating a persistent issue that has not improved over the years under review.
Dr. Mohammad Movahed, a cardiologist at the University of Arizona’s Sarver Heart Center, who led the study, highlighted a potential explanation for the increased vulnerability of men. He suggested that men might seek social and emotional support less frequently in times of stress, thereby prolonging the detrimental effects on their heart health. This observation aligns with the notion that sustained stress can impede recovery and exacerbate heart-related complications, as echoed by Dr. Ilan Wittstein from Johns Hopkins Medicine.
The study’s findings underscore the importance of recognising and addressing the gender disparities in heart health outcomes, particularly concerning ‘broken heart syndrome’. By shedding light on the higher mortality risk faced by men in comparison to women, it highlights the need for tailored care approaches that consider gender-specific factors influencing cardiovascular health. Moving forward, further research and targeted interventions could help mitigate the adverse impacts of stress-induced heart conditions and improve outcomes for all individuals affected by this syndrome.
