John Stamos, popularly known for his role as Uncle Jesse on the hit TV show Full House, recently made headlines with his fiery response during an interview on the Good Guys podcast. The 62-year-old actor was asked a provocative question about whether he would leave his wife, Caitlin McHugh, for his longtime friend and co-star, Lori Loughlin. Stamos did not hold back in his response, displaying his loyalty and commitment to his current relationship.
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Stamos and Loughlin had portrayed the beloved couple, Aunt Becky and Uncle Jesse, on Full House for many years, sparking speculation about a potential real-life romantic connection between the two. However, Stamos clarified during the podcast that their relationship had always been platonic. He fondly reminisced about their friendship, acknowledging that there was a brief moment when they were both single, but ultimately, he chose a different path.

The actor candidly shared his thoughts on Loughlin, describing her as a sweet and kind person. Despite their close bond, Stamos admitted that Loughlin’s niceness was not a match for his more rebellious nature. He also revealed that they may have shared an intimate moment off-camera during their early years of friendship, sparking speculation and nostalgia about their past interactions.

Lori Loughlin recently made headlines with her separation from husband Mossimo Giannulli, after nearly 28 years of marriage. Stamos expressed his support for Loughlin during this challenging time, emphasizing the emotional toll it has taken on her. He highlighted her qualities as a good person, mother, and wife, expressing his sadness over seeing her go through such a difficult period in her life.
When the podcast hosts jokingly probed Stamos about leaving his wife for Loughlin, he responded emphatically, ruling out any possibility of such a scenario. The actor affirmed his commitment to his marriage and staunchly defended his relationship with McHugh. Stamos also addressed Giannulli, Loughlin’s ex-husband, condemning his actions and expressing concern for his well-being.
Stamos did not shy away from criticising Giannulli’s behaviour, labelling him as a “terrible narcissist” and emphasising the need for him to seek help. The actor acknowledged the complexities of the situation, expressing sympathy for Loughlin and the challenges she faces in the aftermath of the separation. His blunt honesty and unwavering support for his friend resonated with fans and drew widespread attention to his comments.
As the interview garnered significant media coverage, fans and observers alike were intrigued by Stamos’ candid revelations and unwavering loyalty to his wife and friend. The actor’s impassioned response served as a reminder of the complexities of relationships and the importance of standing by loved ones during difficult times. Stamos’ words not only shed light on his personal experiences but also sparked discussions about loyalty, friendship, and resilience in the face of adversity.
