Residents of Ladera Ranch, California, are raising concerns regarding the use of pesticides in their community following the alarming diagnosis of six children with Ewing sarcoma, a rare type of cancer that affects bones and soft tissues. Tragically, one of these children, Brody Matteson, passed away in March of this year after a prolonged battle with the disease.
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Ewing sarcoma is notably uncommon, affecting approximately 200 children annually in the United States, according to the American Cancer Society. The occurrence of multiple cases in a single neighbourhood has left many parents questioning whether environmental factors, particularly pesticide exposure, could be a contributing element.

Dustin Matteson, Brody’s father, expressed his concerns, stating, “It seems very, very out of the ordinary for our community to have that many cases here. Something must be causing it, right?” Brody was diagnosed with Ewing sarcoma in August 2024, and during his treatment, he ultimately developed acute myeloid leukaemia, a secondary cancer which led to his untimely death on March 22.
As the community seeks answers, parents are beginning to link their children’s diagnoses to the use of pesticides in the area. While no direct correlation between pesticide exposure and this type of cancer has been definitively proven, studies suggest a potential association. The National Library of Medicine identifies a heightened risk of certain childhood cancers linked to pesticide exposure.
In response to these rising concerns, a meeting was held on June 8 between residents and the Homeowners Association. Matteson reported that the association was attentive to the community’s worries and expressed a willingness to collaborate on finding solutions. “We felt like we received some positive feedback,” he remarked. Ideas for an advisory board consisting of local citizens and landscaping experts were discussed, aimed at developing a more integrated pest management system that prioritises organic methods over synthetic pesticides.
The situation in Ladera Ranch reflects a broader concern about childhood cancer in the area. Paul Imhoff, whose son Reese died from osteosarcoma at age 15 in 2019, echoed similar frustrations, stating, “For ten years now, I’ve been asking the same questions… there’s a higher incidence of kids getting cancer here in Ladera Ranch.” In Reese’s memory, his family established the RISE Foundation, which aims to raise awareness and support for childhood cancer research.
Orange County health officials are currently reviewing these cancer cases to determine if there is a pattern or potential environmental causes. In a recent communication, the Ladera Ranch Maintenance Corporation (LARMAC) expressed its deep sympathy for the affected families. They acknowledged the growing concern among residents regarding the potential health implications of their landscaping practices.
LARMAC reiterated its commitment to reducing synthetic pesticide use through an Integrated Pest Management (IPM) approach, which includes preventive measures, monitoring, and limited application of pest management products when necessary. The organisation noted their continuous efforts to incorporate organic fertilisers and evaluate further reductions in synthetic products.
The association also announced plans to form a committee comprising homeowners, board members, staff, and landscaping professionals. This committee will review landscaping practices and suggest improvements, with an aim to enhance transparency and community engagement.
In their statement, LARMAC emphasised the importance of clear communication with residents regarding landscape management initiatives, promising to adapt their practices based on guidance from public health authorities and other qualified experts. They remain committed to collaborating with the community as new information emerges about health risks associated with environmental factors.
As anxiety grows over the health of their children, parents in Ladera Ranch continue to seek answers and advocate for changes that may potentially safeguard future generations from such tragic diseases. The community, united in its concern, is hopeful for both clarity and solutions in addressing the worrying rise in childhood cancers within their midst.
