At 117 years old, Maria Branyas Morera held the title of the world’s oldest person until her passing in August 2024. Surprisingly, before her death, Morera requested that doctors study her, a wish that was honoured by Dr. Manel Esteller, the chairman of genetics at the University of Barcelona’s School of Medicine. Their findings, published in the Cell Reports Medicine journal on September 24, 2025, shed light on the remarkable factors contributing to Morera’s longevity.
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The study delved into examining Morera’s blood, saliva, urine, and stool to unravel the secrets behind her exceptional health and long life. Dr. Esteller concluded that Morera’s longevity could be pinpointed to a combination of her healthy lifestyle choices and favourable genetic makeup. She abstained from smoking and drinking, maintained an active lifestyle in the countryside, and adhered to a diet rich in Mediterranean components, including olive oil and yogurt. According to Dr. Esteller, Morera possessed gene variants known to safeguard against common health risks such as high cholesterol, dementia, heart disease, and cancer.
Chronic inflammation, a key factor in aging and disease progression, was effectively managed by Morera through her habit of consuming three servings of yogurt daily. Professor Claire Steves from King’s College London, although not directly involved in the study, acknowledged the significance of the research in identifying the genetic and protein factors involved in healthy aging. She underlined that while Morera’s case offers valuable insights, the aging process varies for each individual, and it is essential not to draw broad conclusions solely based on one remarkable case.
In a world where longevity is increasingly being pursued, the study reframes the narrative by emphasising the importance of healthy aging and improving the quality of life rather than solely focusing on extending lifespan. The research underscores the notion that age-related ill health is not an inevitable outcome but rather a product of biological mechanisms that can be influenced and modified. By unravelling the genetic and lifestyle components contributing to Morera’s remarkable lifespan, future studies in healthy aging could be propelled towards new horizons.
Maria Branyas Morera’s life story not only serves as a testament to the possibilities of leading a long and fulfilling existence but also highlights the importance of cherishing each moment and celebrating the gift of life. Despite her advanced age, Morera exuded wisdom and positivity, encapsulated in her words, “Life is not eternal for anyone. At my age, a new year is a gift, a humble celebration, a new adventure, a beautiful journey, a moment of happiness. Let’s enjoy life together.” Her legacy of resilience, vitality, and appreciation for life continues to inspire those who reflect on her remarkable journey.
As the scientific community delves deeper into the realms of aging and longevity, Maria Branyas Morera’s story stands as a beacon of hope and possibility. While not everyone may reach the exceptional age of 117, her story offers valuable insights into the multifaceted interplay of genetics, lifestyle choices, and overall well-being in the journey towards healthy aging. By embracing the lessons gleaned from Morera’s life, individuals and researchers alike are encouraged to explore new avenues in promoting longevity, vitality, and holistic well-being for all.